Exposure to the herbicide atrazine induces oxidative imbalance, morphological damage and decreased survival in juvenile fish
نویسندگان
چکیده
Synthetic herbicides have been intensively used in weed control, although often involved environmental contamination, critically affecting non-target species. However, never was investigated the effect of commercial formulation using atrazine on developing juvenile fish exposed for 35 days. Juveniles (Astyanax altiparanae) (n = 600) were assigned to following ATZ-exposed groups: 0 (CTR-control), 0.56 (ATZ0.56), 1.00 (ATZ1.00), 1.66 (ATZ1.66) and 11.66 (ATZ11.66) μg/L. We found a 36.6% decrease survival rate ATZ11.66 group compared control other groups. from also showed hyperglycemia increased cortisol levels. Increased imbalance oxidative with an increase malondialdehyde (MDA) Carbonylated proteins levels markers muscle, gills, liver. activity antioxidant enzymes superoxide dismutase (SOD) gills SOD catalase (CAT) muscles fish, glutathione S-transferase (GST) activities liver all groups control. The morphological consequences this loss secondary lamella integrity, mucus-secreting cells, hyperplasia, lamellar fusion, as well aneurysms percentage. vascular congestion associated endothelial steatosis, nuclei Our results that exposure ATZ at μg/L can be causing damages decreased Neotropical species great ecological relevance interest.
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ژورنال
عنوان ژورنال: Bioscience Journal
سال: 2023
ISSN: ['1981-3163', '1516-3725']
DOI: https://doi.org/10.14393/bj-v39n0a2023-65784